desktop clients
Unfortunately all the matrix desktop clients we have tested are quite poor from a graphical point of view: very different from whatsapp or telegram ones, and in particular their interface lacks of intuitivity.
Furthermore, the only capable to make a (video or audio) call is Element, while the others work only as messaging app.
mobile clients
There is Element, but I found Schildichat, with a more friendly interface, very similar to WA or Telegram.